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FLASH GENE
Symbol LPAL2 contributors: mct/npt - updated : 08-06-2009
HGNC name lipoprotein, Lp(a)-like 2
HGNC id 21210
Location 6q25.3      Physical location : 160.887.586 - 160.932.156
Synonym name
  • apolipoprotein (a) related gene C
  • apolipoprotein A-like
  • apolipoprotein A-II
    • Synonym symbol(s) APOARGC, APOA2, APOAL, MGC129532, Apo(a)rg-C, RP11-72O9.2
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text part of the cluster SLC22A3-LPAL2-LPA
    STRUCTURE 44.32 kb     10 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    text Variants 1 and 2 encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 2042 14.75 132 - Tregouet (2009)
    10 - 1968 14.75 132 - Tregouet (2009)
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineadrenal gland    
    Reproductivefemale systemuteruscervix  
    Respiratoryrespiratory tracttrachea   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • single kringle domain
    • conjugated HemoP
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme , unknown/unspecified
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to coronary artery disease
    Variant & Polymorphism SNP four SNPs overlapping the SLC22A3-LPAL2-LPA gene cluster associated to risk of coronary artery disease (Tregouet 2009)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS