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FLASH GENE
Symbol HRH2 contributors: - updated : 23-08-2007
HGNC name histamine receptor H2
HGNC id 5183
Location 5q35.3      Physical location : 175.085.039 - 175.113.243
Synonym name
  • gastric receptor 1
  • DNA
    TYPE like-sequence
    STRUCTURE 1.00 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence Promoter
    text structure
  • multiple transcription initiation sites and tissue specific expression
  • MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Skin/Tegumentskin    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • seven transmembrane (7TM) domains
  • HOMOLOGY
    Homologene
    FAMILY G protein coupled receptor superfamily
    CATEGORY receptor G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • activating adenylate cyclase
  • increasing contraction of cardiac muscle
  • stimulating gastric acid secretion
  • involved in the regulate gastrointestinal motility and intestinal secretion
  • possible role in regulating cell growth and differentiation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS