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FLASH GENE

Symbol

CST6

contributors: mct/np - updated : 05-11-2007

HGNC name	cystatin E/M
HGNC id	2478

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral         in metastatic mamary epithelial tumors cells tumoral     --low   in cervical cancer (promoter is silenced by hypermethylation and/or histone deacetylation) (Veena 2008) tumoral     --low   by hypermethylation in renal cell carcinoma (Morris 2010)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS