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FLASH GENE
Symbol ITIH4 contributors: mct/npt - updated : 18-11-2009
HGNC name inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)
HGNC id 6169
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in multiple solid tumors, including breast, colon and lung cancer (Hamm 2008)
constitutional        
in acute ischemic stroke (Kashyap 2009)
Susceptibility
Variant & Polymorphism a C/T single nucleotide polymorphism at IVS17+8 associated with high plasma total cholesterol level
Candidate gene marker of acute ischemic stroke (Kashyap 2009)
Marker
Therapy target
ANIMAL & CELL MODELS