Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

SFRP4

contributors: mct/npt - updated : 02-02-2009

HGNC name	secreted frizzled-related protein 4
HGNC id	10778

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   LOH     in colorectal tumor tumoral     --over   associated with a good prognosis in localized androgen-dependent prostate cancer tumoral     --over   in colorectal carcinoma constitutional     --over   in failing ventricles and ventricular myocardium constitutional     --over   in ADPKD

Susceptibility

Variant & Polymorphism

Candidate gene	DNA methylation markers of Gastric cancer (GC), which may serve as useful markers that may identify a distinct subset of GC (Kang 2008)
Marker
Therapy target	potential therapeutic strategies to modulate Wnt signaling by SFRP4 will be relevant to both localized androgen-dependent prostate cancer and advanced metastatic disease

ANIMAL & CELL MODELS