| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| constitutional
|
|
| --over
|
| |
in retinitis pigmentosa | | tumoral
|
|
|
| loss of function
| |
in colorectal cancer | | tumoral
|
|
| --over
|
|
repressed Wnt target genes and induced changes in the expression of numerous genes related to proliferation, growth and apoptosis in gastric cancer cells  | | tumoral
|
|
| --low
|
| |
silencing leads to oncogenic activation of the Wnt pathway and contributes to cervical cancer progression through the epithelial mesenchymal transition program | | tumoral
|
|
| --low
|
| |
by hypermethylation in primary hepatocellular carcinoma | | constitutional
|
|
|
| loss of function
| |
of SFRP1 and SFRP2, two postulated Wnt antagonists, perturbs retinal neurogenesis | |
