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FLASH GENE
Symbol FOXJ1 contributors: mct - updated : 19-10-2018
HGNC name forkhead box J1
HGNC id 3816
ASSOCIATED DISORDERS
corresponding disease(s) ICS44
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in aggressive ependymoma and choroid plexus tumours
Susceptibility
  • to allergic rhinitis
  • Variant & Polymorphism SNP associated with susceptibility to allergic rhinitis
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • randomization of left/right (L/R) asymetry in mutant mice deficient in HFH4
  • zebrafish Foxj1 homolog, foxj1a, is a target of Hedgehog signaling in the floor plate (Yu 2008)
  • Foxj1-deficient mice develop hydrocephalus