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FLASH GENE

Symbol

FZD9

contributors: mct - updated : 24-08-2011

HGNC name	frizzled homolog 9 (Drosophila)
HGNC id	4047

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive liver FZD9-siRNA could represent a useful therapeutic target for hepatocellular carcinoma (HCC) and hepatoblastoma (HB)

ANIMAL & CELL MODELS

	Fzd9(-/-) mice display low bone mass caused by impaired bone formation
	Frizzled 9-null mice had generally normal gross anatomical hippocampal organization but showed large increases in apoptotic cell death in the developing dentate gyrus