Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

GLA

contributors: mct/npt - updated : 08-11-2023

HGNC name	galactosidase, alpha
HGNC id	4296

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

GLAD

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function with cellular accumulation of sphingolipids may lead to podocyturia and renal loss of function with increased cardiovascular morbidity and mortality in affected patients

Susceptibility

to sporadic Parkinson disease

Variant & Polymorphism other	a variant (NG_007119.1:g.4488C>G) within the promoter region, increasibng the risk of Parkinson disease

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

animal model suggesting a possibility for enzyme remplacement therapy