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FLASH GENE

Symbol

GK

contributors: mct - updated : 07-04-2007

HGNC name	glycerol kinase
HGNC id	4289

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

GKD

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

glycerol kinase-deficient mice, mutant male mice appeared normal at birth, but exhibited postnatal growth retardation, altered fat metabolism with profound hyperglycerolemia and elevated free fatty acids, autonomous glucocorticoid synthesis, and death by 3 to 4 days of age whereas heterozygous females were healthy and biochemically normal