| basic FUNCTION
| may be function))ing in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta |
|
be may promoting neuronal survival |
|
with decorin have a coordinate and cooperative relationship in the regulation of stromal fibrillogenesis  |
|
plays an important role in the highly orchestrated process of dentin mineralization |
|
WISP1 and BGN may functionally interact and control each other activity, thus regulating the differentiation and proliferation of osteogenic cells |
|
required for stable collagen matrix formation of infarct scars and for preservation of cardiac hemodynamic function |
|
promotes osteoblast differentiation and this function is due in part to its ability to positively modulate bone morphogenetic protein (BMP) functions |
|
could facilitate osteoblast functions |
|
BGN core protein is responsible for its function in promoting the BMP2 functions and the glycosaminoglycan component could function as a suppressor in this process |
|
promote bone morphogenetic protein-4 (BMP4) stimulated osteoblastic differentiation |
|
BGN and DCN may have sequential roles in the tendon response to injury |
|
BGN signaling supported fetal membrane remodeling during early gestation in the absence of concomitant changes in TGFB1 levels |
|
BGN has likely a regulatory role in the process of bone formation during fracture healing, and further, that reduced angiogenesis could be the molecular basis |
|
is a factor secreted by peritubular cells to modulate FGFR3c signaling and thus contributes to the regulation of spermatogonial maintenance |
|
BGN and DCN are class I members of the small leucine-rich proteoglycan (SLRP) family that regulate collagen fibril size |
|
BGN is a CADASIL-enriched protein that potentially accumulates in vessels by MTOR-mediated transcriptional activation and/or post-translational accumulation via protein interactions with NOTCH3 and collagen |
|
extracellular matrix proteoglycan that can bind transforming growth factor beta (TGFB1) |
|
is an important structural component of articular cartilage and participates in the assembly of the chondrocyte extracellular matrix through the formation of protein interactions with type VI collagen and large proteoglycan aggregates |
