Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

SLC25A5

contributors: mct - updated : 22-05-2016

HGNC name	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
HGNC id	10991

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

HARTS

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional   deletion     in patients with non-syndromic ntellectual disability (ID) plus some additional features constitutional     --low   caused anemia in a cell-autonomous manner by maturation arrest of erythroid precursors with increased reactive oxygen species and premature deaths constitutional     --over   overexpression of SLC25A5 promoted cell growth and glycolysis

Susceptibility

Variant & Polymorphism

Candidate gene	candidate for cancer therapy based on molecular targeting
Marker
Therapy target
	System Type Disorder Pubmed cancer lung   and that SLC25A5 targeting may be considered a novel strategy for overcoming EGFR-TKI resistance in Non-Small Cell Lung Cancer (PMID: 26883272)

ANIMAL & CELL MODELS