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FLASH GENE

Symbol

DNASE1L1

contributors: - updated : 16-07-2002

HGNC name	deoxyribonuclease I-like 1
HGNC id	2957

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	Xq28      Physical location : 153.629.578 - 153.640.427
Synonym symbol(s)	DNL1L,XAP1 (G4.8),XIB,DRNL
EC.number	3.1.21.-

DNA

TYPE	functioning gene
STRUCTURE	8.00 kb     9 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

status

confirmed

Map	cen - RGCP@ - DNASE1L1 - ATP6AP1 - G6PD - qter
Authors	Parrish (95)
Text	see FLNA

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum cardiac     Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

DNASE-lik catalytic domain and calcium binding and DNA-binding sequences

HOMOLOGY

Homologene

FAMILY

DNASE1 family

CATEGORY

enzyme , DNA associated

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

DNase I-like endonuclease,cardiac and muscle specific

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

nucleic

signaling

DNA

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS