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FLASH GENE
Symbol BMX contributors: - updated : 23-12-2005
HGNC name BMX non-receptor tyrosine kinase
HGNC id 1079
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • SH2, SH3 domains
  • a pleckstrin homology (PH)
  • a catalytic domain
  • a BTK-type zinc finger
    • HOMOLOGY
    Homologene
    FAMILY SRC family
    k1 Tec subfamily
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may play a role in the growth and differentiation of hematopoietic cells
  • may be involved in signal transduction in endocardial and arterial endothelial cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text mesoderm
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binds 1 zinc ion per subunit
    protein
    cell & other
    REGULATION
    activated by IL6 through phosphatidylinositol 3-kinase pathway,in a prostate cancer cell line
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS