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FLASH GENE

Symbol

ZXDB

contributors: mct/npt - updated : 01-07-2008

HGNC name	zinc finger, X-linked, duplicated B
HGNC id	13199

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	5.00 kb     1 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

regionally located

located within approximately 400 kb of ZXDA

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 1 - 5651 84.8 803 - Ross (2005)

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver       highly Urinary bladder       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective adipose     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

ten tandem C2-H2 zinc finger motifs

HOMOLOGY

interspecies	homolog to C.elegans ZK1248.3
	homolog to ZXDA (97 p100)

Homologene

FAMILY

zinc finger protein family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

cooperates with CIITA to promote transcription of MHC class I and MHC class II genes

CELLULAR PROCESS

nucleotide, transcription

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS