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Symbol RENBP contributors: mct - updated : 09-07-2013
HGNC name renin binding protein
HGNC id 9959
Location Xq28      Physical location : 153.200.722 - 153.210.232
Synonym name
  • N acetylglucosamine-2-epimerase
  • GlcNAc 2-epimerase
  • Synonym symbol(s) RNBP, RBP
    EC.number 5.1.3.8
    DNA
    TYPE functioning gene
    STRUCTURE 9.51 kb     11 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map cen - DXS52 - AVPR2 - RENBP - RGCP@ - FLNA - G6PD - F8 - qter
    Authors van den Ouweland (94)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 1507 - 427 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • leucine-zipper domain
  • a domain paarticipating in the specificity for and binding of nucleotides essential to form the catalytic domain
  • mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to murine Renbp
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the regulation of the renin-angiotensin system
  • cellular renin inhibitor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • ATP, dATP, dGTP, dCTP or dTTP stabilize the dimeric form RENBP (GlcNAc 2-epimerase) and inhibited the formation of the renin-RENBP hetero complex
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS