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FLASH GENE

Symbol

HTR2C

contributors: mct - updated : 18-08-2010

HGNC name	5-hydroxytryptamine (serotonin) receptor 2C
HGNC id	5295

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to obesity and increased BMI to metabolic syndrome in patients with schizophrenia

Variant & Polymorphism SNP	increasing the risk of obesity
	HTR2C:c.1-142948(GT)n associated with an increased risk of the metabolic syndrome in patients with schizophrenia (Mulder 2007)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

mouse model lacking MBII-52 snoRNAs shows differences in pre-mRNA processing of the serotonin receptor (Kishore 2010)