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FLASH GENE
Symbol ZNF41 contributors: mct - updated : 09-10-2017
HGNC name zinc finger protein 41
HGNC id 13107
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a KRAB/FBP (Kruppel associated box) at the N terminus
  • a potent transcription repression motif and 18 zinc finger motifs, C2H2 type, Krüppel-like, tandemly arranged at the C terminus
    • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY zinc finger protein family, C2H2 type, Krüppel-like,KRAB subfamily
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in gene-specific transcriptional repression
  • may be playing a critical role for cognitive development
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MRX89
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS