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FLASH GENE

Symbol

ZNF41

contributors: mct - updated : 09-10-2017

HGNC name	zinc finger protein 41
HGNC id	13107

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver         Nervous brain         Skeleton axial skull face maxilla   Visual eye lens

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a KRAB/FBP (Kruppel associated box) at the N terminus
	a potent transcription repression motif and 18 zinc finger motifs, C2H2 type, Krüppel-like, tandemly arranged at the C terminus

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY

zinc finger protein family, C2H2 type, Krüppel-like,KRAB subfamily

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	involved in gene-specific transcriptional repression
	may be playing a critical role for cognitive development

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

MRX89

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS