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FLASH GENE

Symbol

PFKFB1

contributors: mct - updated : 19-04-2008

HGNC name	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
HGNC id	8872

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

mono polymer

homomer , dimer

HOMOLOGY

interspecies

homolog to murine Pfkb1

Homologene

FAMILY

phosphoglycerase mutase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION	involved in fructose 2,6-P2 synthesis and degradation
	activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS