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FLASH GENE
Symbol NAP1L2 contributors: npt/ - updated : 17-06-2005
HGNC name nucleosome assembly protein 1-like 2
HGNC id 7638
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Bpx
intraspecies paralog to NAP1Ls
Homologene
FAMILY
  • nucleosome assembly protein 1 (NAP1) family
    • CATEGORY regulatory , structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • regulating neural cell proliferation with chromatin
  • play overlapping roles in transport and deposition of histone H2A-H2B or H2A variants-H2B dimers on chromatin and nonoverlapping roles in nucleosome disassembly (Okuwaki 2010)
    • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding to chromatin
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to neural tube defects
    Variant & Polymorphism SNP
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS