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FLASH GENE
Symbol ENTPD1 contributors: mct - updated : 05-12-2016
HGNC name ectonucleoside triphosphate diphosphohydrolase 1
HGNC id 3363
ANIMAL & CELL MODELS
  • Entpd1 null mice exhibit decreased synaptic efficacy, presumably due to desensitization P2X1 receptors
  • in rat models of DNA damage, inhibiting Entpd1-driven ATP hydrolysis with POM-1 protected the heart and lung tissues against chemically induced DNA damage