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FLASH GENE
Symbol OPN1LW contributors: mct - updated : 23-12-2017
HGNC name opsin 1 (cone pigments), long-wave-sensitive
HGNC id 9936
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane (7TM) receptor
    • HOMOLOGY
    Homologene
    FAMILY
  • G-protein coupled receptor 1 family
  • Opsin subfamily
    • CATEGORY receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • long wave photon absorption with a maximum at 560 nm (in the yellow-green)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling sensory transduction/vision
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • opsin expression in terminally differentiated mammalian cones remains subject to control by TH (Thyroid hormone)
    • cell & other
    REGULATION
    activated by TH (Liu 2007)
    ASSOCIATED DISORDERS
    corresponding disease(s) CBP , CORDX5
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS