basic FUNCTION
| playing an essential role for the branching of ureteric bud during the development of renal epithelium |
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playing a role in the regulation of the progesterone response of the mature mammary gland |
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may play a role in early ureteric obstruction and subsequent renal maldevelopment |
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expressed in condensing metanephrogenic mesenchyme and arborizing ureteric bud, and plays an important role in kidney development |
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promotes assembly of an H3K4 methyltransferase complex through the ubiquitously expressed nuclear factor PAXIP1 |
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developmental nuclear transcription factor, which is primarily expressed during embryogenesis in kidneys, eyes, ears and in the central nervous system |
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may function as transcriptional regulator, participating in a hierarchical network of gene regulation during embryogenesis |
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transcription factor that is up-regulated during nephrogenesis and becomes silenced in mature epithelium of the glomeruli, the proximal, and distal tubules |
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necessary for mesenchymal to epithelial transformation that occurs within the metanephros |
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suppresses DEFB1 expression in cancer and further implicate PAX2 as a novel therapeutic target for prostate cancer treatment |
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role in optic fissure development and in retinal vasculature patterning |
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plays an important role in kidney development, differentiation, and renal cell proliferation ( |
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pivotal in kidney development and it is implicated in the pathogenesis of renal interstitial fibrosis (RIF) and glomerulosclerosis (GS) |
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promotes proliferation of colon cancer cells through JUN |