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FLASH GENE
Symbol AK1 contributors: npt/ - updated : 24-10-2006
HGNC name adenylate kinase 1
HGNC id 361
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • adenylate and thymidylate kinase domain
    • HOMOLOGY
    interspecies homolog to murine Ak1
    Homologene
    FAMILY
  • adenylate kinase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • adenylate kinase 1 responsible of the phosphorylation of AMP in RBC and production of ADP
  • implicated in adenine nucleotide catabolic pathway and guanine nucleotide pools homeostasis
  • regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides
    • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) AK1
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS