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FLASH GENE
Symbol ALDOB contributors: mct - updated : 28-11-2019
HGNC name aldolase B, fructose-bisphosphate
HGNC id 417
ASSOCIATED DISORDERS
corresponding disease(s) ALDOB
related resource Hereditary Fructose Intolerance/Aldolase
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
promotes colorectal cancer metastasis by facilitating EMT
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • may be a new biomarker associated with mismatch repair (MMR) defieciency and an independent prognostic factor for colon adenocarcinoma
  • biomarker in colorectal cancer
  • Therapy target
    SystemTypeDisorderPubmed
    cancerdigestiveliver
    therapeutic target in colorectal cancer
    ANIMAL & CELL MODELS