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FLASH GENE
Symbol HOXA3 contributors: mct - updated : 22-08-2011
HGNC name homeo box A3
HGNC id 5104
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
helix-turn-helix,DNA binding domain
HOMOLOGY
interspecies homolog to murine Hox-1.5
homolog to Drosophila Zen1,Zen2
Homologene
FAMILY ANTP homeobox family
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • playing a role in a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
  • accelerates wound repair by mobilizing endothelial progenitor cells and attenuating the excessive inflammatory response of chronic wounds
  • apical regulator of haemogenic endothelium
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS