Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

EGR3

contributors: mct/pgu - updated : 09-04-2013

HGNC name	early growth response 3
HGNC id	3240

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to schizophrenia

Variant & Polymorphism SNP	increasing the risk of schizophrenia

Candidate gene	for schizophrenia pathogenesis
Marker
Therapy target
	System Type Disorder Pubmed miscelleaneous vascular   represents a potential therapeutic target in VEGF-mediated vasculopathic diseases

ANIMAL & CELL MODELS

	sensory ataxia and muscle spindle (encapsulated muscle fibers conservated by specialized motor and sensory axons) agenesis,suggesting that type I myotubes are dependent upon Egr3 mediated transcription for proper spindle development
	germline Egr3-deficient mice have physiologic dysautonomia characterized by apoptotic sympathetic neuron death and abnormal innervation to many target tissues