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FLASH GENE

Symbol

EVX1

contributors: npt/ - updated : 08-12-2006

HGNC name	even-skipped homeobox 1
HGNC id	3506

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

helix-turn-helix, DNA binding domain

HOMOLOGY

interspecies	homolog to Drosophila even-skipped pair rule gene 1 (eve)
	ortholog to murine Evx1
	homolog to C.elegans R11G1.5

Homologene

FAMILY

even-skipped homeobox family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	acting as a transcriptional repressor
	regulating gene expression, morphogenesis and differentiation
	playing a role in the specification of neuronal cell types

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

development

text	transcriptional repressor

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS