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FLASH GENE
Symbol EVX1 contributors: npt/ - updated : 08-12-2006
HGNC name even-skipped homeobox 1
HGNC id 3506
Location 7p15.2      Physical location : 27.282.163 - 27.286.192
Synonym name
  • Drosophila even-skipped pair rule gene homolog 1 (murine Evx1)
  • eve, even-skipped homeo box homolog 1 (Drosophila)
    • DNA
    TYPE functioning gene
    STRUCTURE 4.03 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map pter - 3' - EVX1 - 5' - 5' - HOXA13 - 3' - cen
    Authors Faiella (91)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 1858 42.3 407 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • helix-turn-helix, DNA binding domain
    • HOMOLOGY
    interspecies homolog to Drosophila even-skipped pair rule gene 1 (eve)
    ortholog to murine Evx1
    homolog to C.elegans R11G1.5
    Homologene
    FAMILY
  • even-skipped homeobox family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • acting as a transcriptional repressor
  • regulating gene expression, morphogenesis and differentiation
  • playing a role in the specification of neuronal cell types
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS development
    text transcriptional repressor
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS