Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | C1QA | contributors: mct/pgu - updated : 22-10-2013 |
HGNC name | complement component 1, q subcomponent, A chain |
HGNC id | 1241 |
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Corresponding disease |
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Location | 1p36.12 Physical location : 22.963.117 - 22.966.174 | ||
Synonym name | complement component 1, q subcomponent, alpha polypeptide | ||
Synonym symbol(s) | C1q |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
STRUCTURE | 3.06 kb 3 Exon(s) |
Genomic sequence alignment details |
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10 Kb 5' upstream gene genomic sequence study |
MAPPING | cloned | Y | linked | N | status | confirmed |
regionally located | clustered with C1QB, C1QG in the order A, C(G), B |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
| serum | |
at STAGE |
physiological period | fetal, pregnancy |
Text | moderately in placenta and umbilical cord |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP |
mono polymer | heteromer , monomer , dimer |
isoforms | Precursor |
HOMOLOGY |
interspecies | homolog to rattus C1qa (73.5 pc) |
homolog to murine C1qa (70.6 pc) |
intraspecies | homolog to non collagen-like sequence of COLVIII and COLX |
Homologene |
FAMILY |
CATEGORY | immunity/defense , secretory , DNA associated |
SUBCELLULAR LOCALIZATION | extracellular |
intracellular | |
intracellular,cytoplasm |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text |
PATHWAY |
metabolism |
signaling |
cell-cell signaling |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | C1QA |
related resource | C1QAbase - Mutation registry for C1qA deficiency |
Susceptibility |
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Variant & Polymorphism other | |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |