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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PIP

contributors: mct - updated : 08-02-2018

HGNC name	prolactin-induced protein
HGNC id	8993

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   decreased in tape-stripped stratum corneum (SC) samples from atopic dermatitis (AD) patients

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	PIP in stratum corneum (SC) is a potential marker for dysregulated sweating in atopic dermatitis (AD)
	diagnostic biomarker for the histopathological diagnosis of breast cancer
	best independent biomarker able to discriminate between Keratoconus (KC) and controls
Therapy target
	System Type Disorder Pubmed cancer reproductive breast pharmacological inhibition of PIP may therefore serve the bases for both augmentation of existing therapies for hormone-dependent tumors and the development of novel therapeutic approaches for hormone-resistant BCa

ANIMAL & CELL MODELS