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FLASH GENE

Symbol

TG

contributors: SGE/npt - updated : 19-06-2009

HGNC name	thyroglobulin
HGNC id	11764

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

TG

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   mRNA levels are higher in subjects with thyroid disease (Amakawa 2008)

Susceptibility

to autoimmune thyroid disease

Variant & Polymorphism	thyroid hormone synthesis is inhibited because of mutations in the ChEL domain that block protein export from the ER (Lee 2009)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS