Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TG | contributors: SGE/npt - updated : 19-06-2009 |
HGNC name | thyroglobulin |
HGNC id | 11764 |
|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
|
cells |
|
cell lineage
cell lines
| expressed on follicular dendritic cells of thyroid mucosa-associated lymphoid tissue (MALT) lymphoma (Munemasa 2009) | fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
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|
conjugated | GlycoP |
mono polymer | homomer , dimer |
isoforms | Precursor | precursor of thyroid hormone |
HOMOLOGY |
interspecies | homolog to murine Tg (74.3pc) |
homolog to rattus Tg (73.5pc) |
Homologene |
FAMILY |
CATEGORY | storage , signaling hormone |
SUBCELLULAR LOCALIZATION | extracellular |
text | secreted protein |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | hormone |
signaling | hormonal , signal transduction |
|
a component | forming homodimers through the ChEL domains (Lee 2009) |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | TG |
Other morbid association(s) |
|
Susceptibility |
|
Variant & Polymorphism | |
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Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |