Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

RLN2

contributors: mct - updated : 29-11-2014

HGNC name	relaxin 2 (H2)
HGNC id	10027

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in prostate carcinoma constitutional     --low   in diabetes patients tumoral     --over   of RLN2 and S100A4 might be related to the prediction of metastasis potency and poor prognosis for osteosarcoma patients

Susceptibility

to preterm premature rupture of membranes (PPROM) to spontaneous preterm birth (sPTB)

Variant & Polymorphism SNP	rs4742076 was associated significantly with PPROM
	SNP rs3758239 was associated with both PPROM and sPTB

Candidate gene
Marker	detection of RLN2 and S100A4 might be useful in evaluating the outcome of patients with osteosarcoma
Therapy target
	System Type Disorder Pubmed cardiovascular aquired heart failure may offer therapeutic advantages in end-stage heart failure

ANIMAL & CELL MODELS