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Symbol PRPS1L1 contributors: - updated : 29-08-2007
HGNC name phosphoribosyl pyrophosphate synthetase 1-like 1
HGNC id 9463
Location 7p21.1      Physical location : 18.066.401 - 18.067.486
Synonym name
  • ribose-phosphate diphosphokinase catalytic chain III
  • ribose-phosphate pyrophosphokinase III
  • Synonym symbol(s) PRPPL, PRPSL, PRPS3, PRS-III
    EC.number 2.7.6.1
    DNA
    TYPE functioning gene
    STRUCTURE 1.00 kb     1 Exon(s)
    text structure translation of mRNA initiates exclusively at a non-AUG (ACG) codon
    MAPPING cloned N linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY ribose-phosphate pyrophosphokinase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
    magnesium
    protein
    cell & other
    REGULATION
    activated by magnesium and inorganic phosphate
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS