Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PDGFA

contributors: mct - updated : 19-12-2017

HGNC name	platelet-derived growth factor alpha polypeptide
HGNC id	8799

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   expression of PDGFA and its receptor increased in patients with more serious age-related cataracts tumoral       gain of function is frequently upregulated in various cancers

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed neurosensorial visual lens may be a new therapeutic target for cataracts treatment respiratory lung   treatments with both PDGFA and TGFB1 antagonists may result in a better anti-fibrotic outcome for acute lung injury (ALI)-induced lung fibrosis

ANIMAL & CELL MODELS