| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
| deletion
|
|
| |
often codeleted with CDKN2A various malignant cell lines (glioma, lung cancer, leukemia) | | tumoral
|
|
| --low
|
|
in more aggressive breast tumors  | | constitutional
|
|
| --low
|
| |
in hepatocytes in patients with chronic liver disease | | tumoral
|
|
|
| loss of function
| |
significantly associated with advanced tumor stages in Nasopharyngeal Carcinoma | | constitutional
|
|
|
| loss of function
| |
correlated with human diseases including cirrhosis and hepatocellular carcinoma | |
