Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol AMBP contributors: - updated : 18-04-2005
HGNC name alpha-1-microglobulin/bikunin precursor
HGNC id 453
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two BPTI/Kunitz inhibitor domains (58AA motif containing three intrachain disulfide bonds) domains
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY lipocalin family Kernel group)
    CATEGORY immunity/defense , transport carrier
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
    basic FUNCTION inhibition of neurotrophil chemotaxis to endotoxin activated serum
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • expressed in plasma either as a free form or in covalent complexes with albumine IgA and bikunin precursor (ITIL)
  • complexing with ITIH1, ITIH2, ITIH3 or ITIH4, to form alpha type inhibitor (respectively inter- and pre-)
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS