Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | MEST | contributors: mct/ - updated : 04-04-2015 |
HGNC name | mesoderm specific transcript homolog (mouse) |
HGNC id | 7028 |
|
DNA |
TYPE | like-sequence |
SPECIAL FEATURE | overlapping, gene in gene |
text | overlapping of MEST 3' utr and exons 21-24 of COPG2 |
STRUCTURE | 20.10 kb 12 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Promoter |
text structure |
MAPPING | cloned | Y | linked | status | confirmed |
Map | cen - D7S530 - NRF1 - UBE2H - CATR1 - CPA2 - CPA1 - MEST - COPG2 - D7S649 - qter |
Authors | Hayashida (00) |
RNA |
TRANSCRIPTS | type | messenger |
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text | two isoforms : an alternative origin one and one alternative (Kosaki) |
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage | lymphoblastoid cell lines (both isoforms) |
cell lines
fluid/secretion
| |
at STAGE |
physiological period | pregnancy |
Text | hydatidiform mole of androgenetic origin |
IMPRINTING | paternally |
text | in fetal tissues paternal imprinting and in hydatidiform mole of androgenic origin but expressed from both parental alleles (not imprinted) |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
![]() | potential N-linked glycosylation site |
HOMOLOGY |
interspecies | homolog to murine imprinted gene Peg1 |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION
| plasma membrane |
| intracellular |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum |
basic FUNCTION | ![]() |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | ![]() |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | SRS7 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene | Silver-Russel syndrome | |
Marker
Therapy target
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ANIMAL & CELL MODELS |