| basic FUNCTION
| serine/threonine protein kinase, calcium/calmodulin dependent, controling insulin secretion |
|
having important actions on proteins regulating cardiac excitation-contraction coupling |
|
involved in synaptic plasticity in the brain, playing a dual role in excitatory synaptic plasticity: a signaling role during neuronal activity, and an actin-bundling role during the basal state in dendritic spines, thereby affecting both functional and structural plasticity of dendritic spines |
|
phosphorylates MAP2, increasing its binding to microtubules  |
|
required for dendritic growth and branching |
|
its activity regulates the proliferative potential of growth plate chondrocytes |
|
CAMK2A, CAMK2B act in concert, but with distinct functions, to regulate hippocampal synaptic plasticity and learning |
|
specifically activates IL10 promoter activity |
|
distinct role in the induction of anergy in T lymphocytes, by differential regulation of IL10 and IL2 gene transcription suggesting MEF2A as a molecular target which can integrate different calcium signals |
|
is critical for the proper morphological maturation of differentiating oligodendrocytes, an aspect of oligodendrocyte maturation that is mediated to a large extent by changes in the cellular cytoskeleton |
|
critical role of CAMK2B in regulating oligodendrocyte maturation and CNS myelination via an actin-cytoskeleton-regulatory mechanism |
|
. CAMK2A, CAMK2B are essential for various forms of synaptic plasticity |
|
crucial role of CAMK2B in regulating CNS myelination, suggesting that a sodium-dependent glutamate transporter-CAMK2B-actin cytoskeleton axis plays an important role in the regulation of oligodendrocyte maturation and CNS myelination |
|
molecular, temporal and region-specific role of CAMK2B in locomotion |
