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FLASH GENE

Symbol

LIG1

contributors: mct - updated : 10-04-2018

HGNC name	ligase I, DNA, ATP-dependent
HGNC id	6598

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

LIG1

Susceptibility

to non-small cell lung cancer

Variant & Polymorphism other	LIG1 CC genotype was associated with susceptibility to NSCLC, and the AA genotype demonstrated increased radiosensitivity compared to the AC and CC genotypes

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS