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FLASH GENE
Symbol PTCH1 contributors: mct/npt - updated : 21-10-2018
HGNC name patched homolog 1 (Drosophila)
HGNC id 9585
ANIMAL & CELL MODELS
  • inhibition of Shh signaling pathway exacerbated rat ischemic damage caused by permanent middle cerebral artery occlusion, which may be correlated with down-regulated expression of Gli1, Ptch1 and Sod1
  • inactivation of Ptch1 in mice leads to formation of gastrointestinal stromal tumor-like tumors that express Pdgfr&
  • 945;, but not Kit