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FLASH GENE

Symbol

TLE1

contributors: mct/pgu - updated : 19-01-2013

HGNC name	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
HGNC id	11837

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       loss of function epigenetic inactivation contributes to the development of hematologic malignancies by disrupting critical differentiation and growth-suppressing pathways

Susceptibility

Variant & Polymorphism

Candidate gene	marker for synovial sarcoma
Marker
Therapy target

ANIMAL & CELL MODELS