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FLASH GENE
Symbol TSPAN31 contributors: - updated : 26-01-2006
HGNC name tetraspanin 31
HGNC id 10539
DNA
TYPE functioning gene
STRUCTURE 26.00 kb     6 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Reproductivemale systemprostate  highly
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period neonatal
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
four hydrophobic domains
HOMOLOGY
Homologene
FAMILY transmembrane 4 superfamily member (TM4SF)
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
basic FUNCTION
  • putatively involved in growth-related cellular processes
  • playing a role in the regulation of cell development, activation, growth and motility
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • protein constituent of membrane
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   amplification    
    with CDK4, OS9 and PRIM1 in malignant osteosarcoma, glioblastoma and astrocytoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS