Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TSPAN31 contributors: - updated : 26-01-2006
HGNC name tetraspanin 31
HGNC id 10539
Location 12q13-q14      Physical location : 58.138.783 - 58.142.025
Synonym name
  • sarcoma amplified sequence
  • transmembrane 4 protein
    • Synonym symbol(s) SAS
    DNA
    TYPE functioning gene
    STRUCTURE 26.00 kb     6 Exon(s)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Reproductivemale systemprostate  highly
    Visualeye   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period neonatal
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    		four hydrophobic domains
    HOMOLOGY
    Homologene
    FAMILY transmembrane 4 superfamily member (TM4SF)
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • putatively involved in growth-related cellular processes
  • playing a role in the regulation of cell development, activation, growth and motility
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • protein constituent of membrane
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   amplification    
    with CDK4, OS9 and PRIM1 in malignant osteosarcoma, glioblastoma and astrocytoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS