Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

LIMK1

contributors: mct - updated : 05-09-2019

HGNC name	LIM domain kinase 1
HGNC id	6613

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

WBS

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional   deletion     in Williams syndrome tumoral     --over   significantly promoted colon cancer cell migration and invasion

Susceptibility

to intracranial aneurysm

Variant & Polymorphism SNP	promoter C(-187)T SNP increasing the risk of intracranial aneurysm

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed immunology autoimmune   downregulating LIMK1 expression may provide a novel therapy for suppression and prevention of ocular inflammation and fibrosis

ANIMAL & CELL MODELS