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FLASH GENE
Symbol IFNA2 contributors: mct - updated : 30-05-2015
HGNC name interferon, alpha 2
HGNC id 5423
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to C.elegans y54g2a.t
Homologene
FAMILY interferon alpha,beta and delta family
CATEGORY immunity/defense
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • IFNL1, and IFNA2 differ in their ability to modulate IL12 production by TLR-activated macrophages and exhibit differential regulation of the IFNGR1 expression
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • RS4 is a novel USP18-binding protein that can be used to boost the host innate immunity to control HCV, and potentially other viruses that are sensitive to IFNA2
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS