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FLASH GENE
Symbol AOAH contributors: npt/ - updated : 23-05-2005
HGNC name acyloxyacyl hydrolase (neutrophil)
HGNC id 548
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Endocrinethyroid    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
Lymphoid/Immunemacrophage
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • lipase consensus sequence in large subunit saposin homology region in small subunit
    • mono polymer heteromer , dimer
    isoforms Precursor precursor of two disulfide-linked subunits
    HOMOLOGY
    interspecies homolog to murine Aoah
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • specifically hydrolyzing the secondary acyl chains of the liposaccharide found in the walls of gram-negative bacteria
  • two-subunit lipase
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS inflammation
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS