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FLASH GENE

Symbol

AOAH

contributors: npt/ - updated : 23-05-2005

HGNC name	acyloxyacyl hydrolase (neutrophil)
HGNC id	548

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	211.42 kb     21 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

text	precursor of two disulfide-linked subunits

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed AOAH 21 - 2474 65.1 575 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon     Endocrine thyroid

cells

System Cell Pubmed Species Stage Rna symbol Blood/Hematopoietic leukocyte Lymphoid/Immune macrophage

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

lipase consensus sequence in large subunit saposin homology region in small subunit

mono polymer

heteromer , dimer

isoforms

Precursor

precursor of two disulfide-linked subunits

HOMOLOGY

interspecies

homolog to murine Aoah

Homologene

FAMILY

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION	specifically hydrolyzing the secondary acyl chains of the liposaccharide found in the walls of gram-negative bacteria
	two-subunit lipase

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

inflammation

PATHWAY

metabolism

lipid/lipoprotein

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS